Title : Effects of menthol on the pharmacokinetics of triazolam and phenytoin.

Pub. Date : 2015

PMID : 25757928






2 Functional Relationships(s)
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1 We have previously shown that menthol attenuates the anticoagulant effect of warfarin by increasing the expression levels of CYP3A and CYP2C in the liver. Menthol cytochrome P450, family 2, subfamily c, polypeptide 29 Mus musculus
2 Similarly, the AUC of phenytoin was lower and the hepatic CYP2C expression level was higher in the menthol-treated group. Menthol cytochrome P450, family 2, subfamily c, polypeptide 29 Mus musculus