Pub. Date : 2015 Apr
PMID : 25742870
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Since GS is an ATP-dependent enzyme, mitochondrial dysfunction might contribute to reduced activity, which might also account for the increased metabolism of glutamate via the GABA shunt, a metabolic pathway to bypass intra-mitochondrial alpha-ketoglutarate-dehydrogenase, resulting in elevated GABA levels. | Adenosine Triphosphate | glutamate-ammonia ligase (glutamine synthetase) | Mus musculus |