Title : Synthesis and in vitro antiproliferative activity of amido and amino analogues of the marine alkaloid isogranulatimide.

Pub. Date : 2015 Apr

PMID : 25735892






2 Functional Relationships(s)
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1 Granulatimide and isogranulatimide are marine alkaloids that have been shown to inhibit checkpoint kinase 1 (Chk1), a key protein in the DNA damage response and an emerging target for anticancer therapeutics. Alkaloids checkpoint kinase 1 Homo sapiens
2 Granulatimide and isogranulatimide are marine alkaloids that have been shown to inhibit checkpoint kinase 1 (Chk1), a key protein in the DNA damage response and an emerging target for anticancer therapeutics. Alkaloids checkpoint kinase 1 Homo sapiens