Title : Drug repositioning for gynecologic tumors: a new therapeutic strategy for cancer.

Pub. Date : 2015

PMID : 25734181






1 Functional Relationships(s)
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1 Metformin, an antidiabetic drug, is effective for endometrial cancer through inhibition of the PI3K-Akt-mTOR pathway by activating LKB1-AMPK and reduction of insulin and insulin-like growth factor-1 due to AMPK activation. Metformin serine/threonine kinase 11 Homo sapiens