Title : SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx.

Pub. Date : 2015 Mar 3

PMID : 25730848






2 Functional Relationships(s)
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1 Unlike NOX-dependent NETosis, NOX-independent NETosis is accompanied by a substantially lower level of activation of ERK and moderate level of activation of Akt, whereas the activation of p38 is similar in both pathways. nicotine 1-N-oxide AKT serine/threonine kinase 1 Homo sapiens
2 Despite the differential activation, both NOX-dependent and -independent NETosis require Akt activity. nicotine 1-N-oxide AKT serine/threonine kinase 1 Homo sapiens