Title : Jadomycin breast cancer cytotoxicity is mediated by a copper-dependent, reactive oxygen species-inducing mechanism.

Pub. Date : 2015 Mar

PMID : 25729577






1 Functional Relationships(s)
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1 Specific inhibitors of the antioxidant enzymes, superoxide dismutase 1, glutathione S-transferase, and thioredoxin reductase, but not catalase, enhanced jadomycin-mediated ROS generation and anticancer activity. Reactive Oxygen Species glutathione S-transferase kappa 1 Homo sapiens