Title : Effect of flunixin meglumine and firocoxib on ex vivo cyclooxygenase activity in horses undergoing elective surgery.

Pub. Date : 2015 Mar

PMID : 25710756






2 Functional Relationships(s)
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1 RESULTS: At 2 and 24 hours after NSAID administration, COX-1 activity was reduced, compared with baseline activity, for the flunixin meglumine group only and relative COX-1 activity was significantly greater for the firocoxib group, compared with that for the flunixin meglumine group. firocoxib cytochrome c oxidase subunit I Equus caballus
2 CONCLUSIONS AND CLINICAL RELEVANCE: Compared with flunixin meglumine, firocoxib had COX-1-sparing effects ex vivo in equine patients that underwent elective surgery. firocoxib cytochrome c oxidase subunit I Equus caballus