Pub. Date : 1989 Aug 21
PMID : 2570626
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NMDA receptor activation by residual glutamate in glutamine preparations: a cautionary note regarding weak NMDA receptor agonists. | Glutamic Acid | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |
| 2 | However, NMDA receptor activation induced by glutamine probably represented activity of residual glutamate because: (a) recrystallization of glutamine reduced residual glutamate levels (measured by HPLC analysis) and NMDA receptor activation by comparable amounts; and (b) glutamate at concentrations close to those predicted to be present in glutamine preparations elicited currents of similar amplitudes. | Glutamic Acid | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |
| 3 | However, NMDA receptor activation induced by glutamine probably represented activity of residual glutamate because: (a) recrystallization of glutamine reduced residual glutamate levels (measured by HPLC analysis) and NMDA receptor activation by comparable amounts; and (b) glutamate at concentrations close to those predicted to be present in glutamine preparations elicited currents of similar amplitudes. | Glutamic Acid | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |
| 4 | Our data indicate that residual glutamate at levels of less than 0.05% are sufficient to confound studies of weak NMDA receptor agonists. | Glutamic Acid | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |