Pub. Date : 2015 Jun
PMID : 25692452
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Open-channel block of SCN5A channels was concentration dependent, with bupivacaine being approximately 4.5-fold more potent than ropivacaine (IC50 = 69.5 +- 8.2 muM vs IC50 = 322.2 +- 29.9 muM). | Bupivacaine | latexin | Homo sapiens |
| 2 | RESULTS: Open-channel block of SCN5A channels was concentration dependent, with bupivacaine being approximately 4.5-fold more potent than ropivacaine (IC50 = 69.5 +- 8.2 muM vs IC50 = 322.2 +- 29.9 muM). | Bupivacaine | latexin | Homo sapiens |
| 3 | In their inactivated state, SCN5A channels were slightly more sensitive toward bupivacaine than toward ropivacaine (IC50 = 2.18 +- 0.16 muM vs IC50 = 2.73 +- 0.27 muM). | Bupivacaine | latexin | Homo sapiens |