Pub. Date : 2015 Apr
PMID : 25691431
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis. | Sphingolipids | ORMDL sphingolipid biosynthesis regulator 3 | Homo sapiens |
| 2 | Here we test the notion that elevated levels of ORMDL3 decrease sphingolipid biosynthesis. | Sphingolipids | ORMDL sphingolipid biosynthesis regulator 3 | Homo sapiens |
| 3 | Although sphingolipid biosynthesis was not decreased by elevated ORMDL3 expression, the steady state mass levels of all major sphingolipids were marginally decreased by low level ORMDL3 over-expression in HBECs. | Sphingolipids | ORMDL sphingolipid biosynthesis regulator 3 | Homo sapiens |
| 4 | These data indicate that the contribution of ORMDL3 to asthma risk may involve changes in sphingolipid metabolism, but that the connection is complex. | Sphingolipids | ORMDL sphingolipid biosynthesis regulator 3 | Homo sapiens |