Title : Targeting cancer stem cells in breast cancer: potential anticancer properties of 6-shogaol and pterostilbene.

Pub. Date : 2015 Mar 11

PMID : 25686711






1 Functional Relationships(s)
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1 Analysis of the underlying mechanism showed that 6-S and PTE decreased the expression of the surface antigen CD44 on BCSCs and promoted beta-catenin phosphorylation through the inhibition of hedgehog/Akt/GSK3beta signaling, thus decreasing the protein expression of downstream c-Myc and cyclin D1 and reducing BCSC stemness. pterostilbene cyclin D1 Homo sapiens