Title : Effects of acute and sustained administration of vortioxetine on the serotonin system in the hippocampus: electrophysiological studies in the rat brain.

Pub. Date : 2015 Jul

PMID : 25665528






1 Functional Relationships(s)
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1 RATIONALE: Vortioxetine is a novel multimodal antidepressant that is a 5-HT1B receptor partial agonist, a 5-HT1A receptor agonist, an inhibitor of the serotonin (5-HT) transporter, and a 5-HT1D, 5-HT3, and 5-HT7 receptor antagonist in vitro. Vortioxetine 5-hydroxytryptamine receptor 1D Rattus norvegicus