Title : Effects of acute and sustained administration of vortioxetine on the serotonin system in the hippocampus: electrophysiological studies in the rat brain.

Pub. Date : 2015 Jul

PMID : 25665528






1 Functional Relationships(s)
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1 Long-term administration of vortioxetine and escitalopram (both at 5 mg/kg/day) induced an increase of tonic activation of the 5-HT1A receptors in CA3 pyramidal neurons, resulting in an increase in 5-HT transmission. Vortioxetine carbonic anhydrase 3 Rattus norvegicus