Pub. Date : 2015 Oct 1
PMID : 25659586
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We report here the ability of p73 to upregulate the expression of the A2B receptor, a recently characterized p53 target that effectively promotes cell death in response to extracellular adenosine--a metabolite that accumulates during various forms of cellular stress. | Adenosine | tumor protein p53 | Homo sapiens |
| 2 | We therefore propose an alternate and distinct p53-independent pathway to stimulate programmed cell death involving p73-mediated engagement of adenosine signalling. | Adenosine | tumor protein p53 | Homo sapiens |