Title : The purine analog fludarabine acts as a cytosolic 5'-nucleotidase II inhibitor.

Pub. Date : 2015 Mar 15

PMID : 25656700






1 Functional Relationships(s)
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1 In vitro studies using the wild type recombinant cN-II demonstrated that fludarabine inhibited enzymatic activity in a mixed manner (Ki 0.5 mM and Ki" 9 mM), whereas no inhibition was observed with clofarabine and cladribine. Clofarabine 5'-nucleotidase, cytosolic II Homo sapiens