Title : Exploration of the active site of β4GalT7: modifications of the aglycon of aromatic xylosides.

Pub. Date : 2015 Mar 21

PMID : 25655827






2 Functional Relationships(s)
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1 The biosynthesis of GAG chains is initiated by xylosylation of the core protein followed by galactosylation by the galactosyltransferase beta4GalT7. Glycosaminoglycans beta-1,4-galactosyltransferase 7 Homo sapiens
2 Some beta-d-xylosides, such as 2-naphthyl beta-d-xylopyranoside, can induce GAG synthesis by serving as acceptor substrates for beta4GalT7 and by that also compete with the GAG synthesis on core proteins. Glycosaminoglycans beta-1,4-galactosyltransferase 7 Homo sapiens