Title : N-methyl-D-aspartate/glycine and quisqualate/kainate receptors expressed in Xenopus oocytes: antagonist pharmacology.

Pub. Date : 1989 Mar

PMID : 2564633






3 Functional Relationships(s)
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1 Schild analysis of currents evoked by NMDA indicated that the EAA receptor antagonist D-2-amino-5-phosphonovalerate (D-APV) exerted a competitive block of the oocyte NMDA receptor, because the Schild regression was linear with a slope not significantly different from unity (1.03 +/- 0.025) up to 100 microM D-APV. 2-amino-4-oxo-5-phosphonopentanoic acid glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
2 Schild analysis of currents evoked by NMDA indicated that the EAA receptor antagonist D-2-amino-5-phosphonovalerate (D-APV) exerted a competitive block of the oocyte NMDA receptor, because the Schild regression was linear with a slope not significantly different from unity (1.03 +/- 0.025) up to 100 microM D-APV. 2-amino-4-oxo-5-phosphonopentanoic acid glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
3 Schild analysis of currents evoked by NMDA indicated that the EAA receptor antagonist D-2-amino-5-phosphonovalerate (D-APV) exerted a competitive block of the oocyte NMDA receptor, because the Schild regression was linear with a slope not significantly different from unity (1.03 +/- 0.025) up to 100 microM D-APV. 2-amino-4-oxo-5-phosphonopentanoic acid glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis