Title : Characterization of the interaction of the novel antihypertensive etamicastat with human dopamine-β-hydroxylase: comparison with nepicastat.

Pub. Date : 2015 Mar 15

PMID : 25641750






1 Functional Relationships(s)
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1 In conclusion, etamicastat and nepicastat behave as multisubstrate DBH inhibitors, binding reversibly and preferentially to the reduced form of the enzyme, and simultaneously at the substrate and oxygen binding sites. Oxygen dopamine beta-hydroxylase Homo sapiens