Pub. Date : 2014 Oct 31
PMID : 25628381
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interestingly, 7,8-DHF significantly attenuated LPS-induced reduction of p-TrkB and spine densities in the CA3, DG, and PFC, whereas ANA-12 significantly attenuated LPS-induced increases of p-TrkB and spine density in the NAc. | 6,7-dihydroxyflavone | carbonic anhydrase 3 | Mus musculus |
| 2 | CONCLUSIONS: The results suggest that LPS-induced inflammation may cause depression-like behavior by altering BDNF and spine density in the CA3, DG, PFC, and NAc, which may be involved in the antidepressant effects of 7,8-DHF and ANA-12, respectively. | 6,7-dihydroxyflavone | carbonic anhydrase 3 | Mus musculus |