Title : Salvianolic Acid B Protects Normal Human Dermal Fibroblasts Against Ultraviolet B Irradiation-Induced Photoaging Through Mitogen-Activated Protein Kinase and Activator Protein-1 Pathways.

Pub. Date : 2015 Jul-Aug

PMID : 25626519






2 Functional Relationships(s)
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1 Our results show that SAB significantly inhibited the UVB-induced expression of metalloproteinases-1 (MMP-1) and interleukin-6 (IL-6) while promoting the production of type I procollagen and transforming growth factor beta1 (TGF-beta1). salvianolic acid B matrix metallopeptidase 1 Homo sapiens
2 These results indicate that SAB downregulates UV-induced MMP-1 expression by inhibiting Mitogen-activated protein kinase (MAPK) signaling pathways and activator protein-1 (AP-1) activation. salvianolic acid B matrix metallopeptidase 1 Homo sapiens