Title : SHP-1 is a negative regulator of epithelial-mesenchymal transition in hepatocellular carcinoma.

Pub. Date : 2015 Oct 8

PMID : 25619838






2 Functional Relationships(s)
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1 Depletion of SHP-1 could induce a more increase in TGF-beta1-induced p-STAT3(Tyr-705) and EMT characteristics, further supporting the mechanism that suppression of TGF-beta1-induced EMT is dependent on SHP-1-mediated STAT3 inactivation. Tyrosine transforming growth factor beta 1 Homo sapiens
2 Depletion of SHP-1 could induce a more increase in TGF-beta1-induced p-STAT3(Tyr-705) and EMT characteristics, further supporting the mechanism that suppression of TGF-beta1-induced EMT is dependent on SHP-1-mediated STAT3 inactivation. Tyrosine transforming growth factor beta 1 Homo sapiens