Title : The antibody atliximab attenuates collagen-induced arthritis by neutralizing AIMP1, an inflammatory cytokine that enhances osteoclastogenesis.

Pub. Date : 2015 Mar

PMID : 25617125






1 Functional Relationships(s)
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1 Taken together, our findings suggest that AIMP1 exacerbates RA by promoting inflammation and osteoclastogenesis and that atliximab could be developed as a therapeutic antibody to target inflammatory diseases, including RA. Radium aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 Mus musculus