Title : Resistance of SMMC-7721 hepatoma cells to etoposide in hypoxia is reversed by VEGF inhibitor.

Pub. Date : 2015 May

PMID : 25607114






3 Functional Relationships(s)
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Protein Name
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1 Resistance of SMMC-7721 hepatoma cells to etoposide in hypoxia is reversed by VEGF inhibitor. smmc vascular endothelial growth factor A Homo sapiens
2 Increased levels of hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) were observed when SMMC-7721 cells were exposed to hypoxia, and exposure of tumor cells to hypoxia impaired etoposide-induced DNA damage, as indicated by the failure of upregulation of gammaHA2X. smmc vascular endothelial growth factor A Homo sapiens
3 Increased levels of hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) were observed when SMMC-7721 cells were exposed to hypoxia, and exposure of tumor cells to hypoxia impaired etoposide-induced DNA damage, as indicated by the failure of upregulation of gammaHA2X. smmc vascular endothelial growth factor A Homo sapiens