Title : Metformin inhibits tumor growth by regulating multiple miRNAs in human cholangiocarcinoma.

Pub. Date : 2015 Feb 20

PMID : 25605008






2 Functional Relationships(s)
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1 Further we confirmed that metformin upregulated Drosha to modulate these miRNAs expression. Metformin drosha ribonuclease III Homo sapiens
2 Our results elucidated that metformin inhibited CCA tumor growth via the regulation of Drosha-mediated multiple carcinogenic miRNAs expression and comprehensive evaluation of these miRNAs expression could be more efficient to predict the prognosis. Metformin drosha ribonuclease III Homo sapiens