Pub. Date : 2015 Feb 20
PMID : 25603047
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Type II anti-CD20 mAb-induced lysosome mediated cell death is mediated through a ceramide-dependent pathway. | Ceramides | keratin 20 | Homo sapiens |
| 2 | Herein, we reveal that the induction of ceramide generation by anti-CD20 mAbs directly correlates with their ability to induce PCD. | Ceramides | keratin 20 | Homo sapiens |
| 3 | These findings provide further insights into a previously unrecognized role for ceramide generation in mediating PCD evoked by type II anti-CD20 mAbs in Burkitt"s lymphoma cells. | Ceramides | keratin 20 | Homo sapiens |