Title : β-elemene inhibited expression of DNA methyltransferase 1 through activation of ERK1/2 and AMPKα signalling pathways in human lung cancer cells: the role of Sp1.

Pub. Date : 2015 Mar

PMID : 25598321






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Interestingly, metformin not only reversed the effect of beta-elemene on phosphorylation of Akt but also strengthened the beta-elemene-reduced DNMT1. Metformin DNA methyltransferase 1 Homo sapiens
2 Metformin augments the effect of beta-elemene by blockade of Akt signalling and additively inhibition of DNMT1 protein expression. Metformin DNA methyltransferase 1 Homo sapiens