Title : Sp1 regulates Raf/MEK/ERK-induced p21(CIP1) transcription in TP53-mutated cancer cells.

Pub. Date : 2015 Mar

PMID : 25595558






1 Functional Relationships(s)
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1 Consistent with this observation in SK-MEL28 cells, Sp1 was necessary for the tamoxifen-regulated Raf-1:ER to induce p21(CIP1) transcription in U251 cells, in which TP53 is mutated. Tamoxifen tumor protein p53 Homo sapiens