Title : CYP3A5 regulates prostate cancer cell growth by facilitating nuclear translocation of AR.

Pub. Date : 2015 Apr 1

PMID : 25586052






1 Functional Relationships(s)
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1 CYP3A5 siRNA inhibited growth in response to DHT and R1881 treatment in LNCaP and C4-2 by decreasing nuclear AR localization and resulting in diminished PSA and TMPRSS2 expression. Dihydrotestosterone androgen receptor Mus musculus