Title : Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site.

Pub. Date : 2015 Feb 12

PMID : 25581127






1 Functional Relationships(s)
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1 By appending dual tail groups onto the par excellence CA inhibitor acetazolamide, compounds that may interact with the distinct hydrophobic and hydrophilic halves of the CA II active site were prepared. Acetazolamide carbonic anhydrase 2 Homo sapiens