Title : Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of Aβ oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells.

Pub. Date : 2015

PMID : 25565776






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Coff or Caff, plus Mel inhibited GSK3beta, Akt, PI3K p55, and Tau phosphorylation but enhanced PI3K p85 and Erk1/2 phosphorylation in N2a/APP cells. Melatonin mitogen-activated protein kinase 3 Mus musculus