Title : A novel post-translational modification of nucleolin, SUMOylation at Lys-294, mediates arsenite-induced cell death by regulating gadd45α mRNA stability.

Pub. Date : 2015 Feb 20

PMID : 25561743






1 Functional Relationships(s)
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1 In response to arsenic exposure, nucleolin-SUMO was induced and promoted its binding with gadd45alpha mRNA, which increased gadd45alpha mRNA stability and protein expression, subsequently causing GADD45alpha-mediated cell death. Arsenic nucleolin Homo sapiens