Pub. Date : 2014
PMID : 25556455
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dexamethasone disrupts cytoskeleton organization and migration of T47D Human breast cancer cells by modulating the AKT/mTOR/RhoA pathway. | Dexamethasone | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Moreover, the effect of Dex on cell migration and cytoskeleton may be mediated by AKT/ mTOR/RhoA pathway. | Dexamethasone | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | CONCLUSIONS: Dex in T47D human breast cancer cells could effectively inhibit cell migration by disrupting the cytoskeletal dynamic organization, which may be mediated by the AKT/mTOR/RhoA pathway. | Dexamethasone | AKT serine/threonine kinase 1 | Homo sapiens |