Title : Transglutaminase 2 is involved in homocysteine-induced activation of human THP-1 monocytes.

Pub. Date : 2015 Mar

PMID : 25547897






1 Functional Relationships(s)
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1 A five-day incubation with Hcy (~25 muM) increased reactive oxygen species, peroxide lipids, as well as 8-hydroxyguanosine levels by twofold, and decreased the endogenous cell antioxidant defenses, that is reduced glutathione, by 50% in Hcy-exposed cultures compared with controls (p < 0.01). Glutathione latexin Homo sapiens