Pub. Date : 2015 Jul
PMID : 25545366
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | miR-1470 mediates lapatinib induced p27 upregulation by targeting c-jun. | Lapatinib | interferon alpha inducible protein 27 | Homo sapiens |
| 2 | Our previous study indicated that lapatinib induces p27-dependent G(1) arrest through both transcriptional and post-translational mechanisms. | Lapatinib | interferon alpha inducible protein 27 | Homo sapiens |
| 3 | Using miRNA microarray technology and quantitative RT-PCR, we further investigated the potential miRNAs that involved in p27 upregulation and Her-2 signaling pathway alteration with lapatinib treatment. | Lapatinib | interferon alpha inducible protein 27 | Homo sapiens |
| 4 | Taken together, the present study provided the first evidences that miR-1470 mediated lapatinib induced p27 upregulation by targeting c-jun. | Lapatinib | interferon alpha inducible protein 27 | Homo sapiens |