Title : Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity.

Pub. Date : 2015 Mar

PMID : 25529920






1 Functional Relationships(s)
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1 Inhibition of Nox2 prevented superoxide overproduction, restored lysosome acidification and enzyme activity, and reduced autophagosome accumulation in palmitate-treated CMs. Superoxides cytochrome b-245, beta polypeptide Mus musculus