Pub. Date : 2015 Mar
PMID : 25524470
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Deferoxamine inhibits TRAIL-mediated apoptosis via regulation of autophagy in human colon cancer cells. | Deferoxamine | TNF superfamily member 10 | Homo sapiens |
| 2 | The present study investigated the effects of DFO on TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in colon cancer cells and and the mechanism involved. | Deferoxamine | TNF superfamily member 10 | Homo sapiens |
| 3 | The present study investigated the effects of DFO on TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in colon cancer cells and and the mechanism involved. | Deferoxamine | TNF superfamily member 10 | Homo sapiens |
| 4 | The experimental results showed that DFO treatment inhibited TRAIL-mediated cancer cell apoptosis by increasing Akt activation and decreasing caspase activation in human colon cancer cells. | Deferoxamine | TNF superfamily member 10 | Homo sapiens |
| 5 | Furthermore, DFO treatment induced autophagy flux, and chloroquine, an autophagy inhibitor, blocked DFO-mediated inhibition of TRAIL-induced apoptosis. | Deferoxamine | TNF superfamily member 10 | Homo sapiens |
| 6 | The present study demonstrated that DFO inhibited TRAIL-mediated tumor cell death via the autophagy pathway, and the results suggest that potent anticancer agent, DFO, can be an inhibitor against antitumor therapy including TRAIL protein. | Deferoxamine | TNF superfamily member 10 | Homo sapiens |
| 7 | The present study demonstrated that DFO inhibited TRAIL-mediated tumor cell death via the autophagy pathway, and the results suggest that potent anticancer agent, DFO, can be an inhibitor against antitumor therapy including TRAIL protein. | Deferoxamine | TNF superfamily member 10 | Homo sapiens |
| 8 | The present study demonstrated that DFO inhibited TRAIL-mediated tumor cell death via the autophagy pathway, and the results suggest that potent anticancer agent, DFO, can be an inhibitor against antitumor therapy including TRAIL protein. | Deferoxamine | TNF superfamily member 10 | Homo sapiens |
| 9 | The present study demonstrated that DFO inhibited TRAIL-mediated tumor cell death via the autophagy pathway, and the results suggest that potent anticancer agent, DFO, can be an inhibitor against antitumor therapy including TRAIL protein. | Deferoxamine | TNF superfamily member 10 | Homo sapiens |