Pub. Date : 2014 Dec 17
PMID : 25517874
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Activation of RidA chaperone function by N-chlorination. | Nitrogen | reactive intermediate imine deaminase A homolog | Homo sapiens |
| 2 | N-chlorination increases hydrophobicity of RidA and promotes binding to a wide spectrum of unfolded cytosolic proteins. | Nitrogen | reactive intermediate imine deaminase A homolog | Homo sapiens |
| 3 | HOCl-mediated N-chlorination thus is a cysteine-independent post-translational modification that reversibly turns RidA into an effective chaperone holdase, which plays a crucial role in the protection of cytosolic proteins during oxidative stress. | Nitrogen | reactive intermediate imine deaminase A homolog | Homo sapiens |