Title : Self-induction of 1,25-dihydroxyvitamin D3 metabolism limits receptor occupancy and target tissue responsiveness.

Pub. Date : 1989 Sep 25

PMID : 2550427






1 Functional Relationships(s)
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1 This apparent reduction in the affinity of VDR for 1,25-(OH)2D3 was due to degradation of free 1,25-(OH)2[3H]D3 which occurred during whole cell saturation assay. Cholecalciferol vitamin D receptor Homo sapiens