Title : Inhibitory effects of imatinib on vitamin D₃ synthesis in human keratinocytes.

Pub. Date : 2015 Apr

PMID : 25501030

1 Functional Relationships(s)
Compound Name
Protein Name
1 Based on interaction studies of imatinib with the cytochrome P450 (CYP450) inhibitors VID400 and ketoconazole, it is proposed that imatinib may interfere with the vitamin D3 cascade due to its metabolism by CYP27B1, which is involved in vitamin D3 metabolism. Cholecalciferol cytochrome P450 family 27 subfamily B member 1 Homo sapiens