Title : Down-regulation of carboxylesterases 1 and 2 plays an important role in prodrug metabolism in immunological liver injury rats.

Pub. Date : 2015 Feb

PMID : 25499727






1 Functional Relationships(s)
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1 The decreased activities of CES1 and CES2 were preliminarily assessed by the hydrolysis assay for their common substrate p-nitrophenyl acetate (PNPA) with rat hepatic microsomal enzyme. 4-nitrophenyl acetate carboxylesterase 1E Rattus norvegicus