Pub. Date : 2015 Feb 28
PMID : 25497868
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment with UBS109, EF31 or curcumin inhibited HSP90, NF-kappaB, and HIF-1alpha transcription in PC cell lines. | Curcumin | heat shock protein 90 alpha family class A member 1 | Homo sapiens |
| 2 | Finally, we demonstrate for the first time that curcumin analogues EF31 and UBS109 induce the downregulation of HIF-1alpha, Hsp90, COX-2 and VEGF in tumor samples from xenograft models compared to untreated xenografts. | Curcumin | heat shock protein 90 alpha family class A member 1 | Homo sapiens |