Title : Activity-guided investigation of Carissa carandas (L.) roots for anti-inflammatory constituents.

Pub. Date : 2015

PMID : 25496183






1 Functional Relationships(s)
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1 Bioassay guided fractionation of methanol extract based on inhibitory potential towards proinflammatory mediators (TNF-alpha, IL-1beta and nitric oxide (NO)) led to the identification of stigmasterol (1), lupeol (2), oleanolic acid (3), carissone (4) and scopoletin (5) as potential anti-inflammatory agents. Stigmasterol interleukin 1 beta Homo sapiens