Title : Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoids.

Pub. Date : 2015

PMID : 25492813






5 Functional Relationships(s)
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1 Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoids. Retinoids cytochrome P450 family 26 subfamily A member 1 Homo sapiens
2 Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoids. Retinoids cytochrome P450 family 26 subfamily A member 1 Homo sapiens
3 Hence, CYP26A1, the main atRA hydroxylase, may function either to deplete bioactive retinoids or to form active metabolites. Retinoids cytochrome P450 family 26 subfamily A member 1 Homo sapiens
4 These data support the role of CYP26A1 to clear bioactive retinoids, and suggest that the enzyme forming active 4-oxo-atRA may be important in modulating retinoid action. Retinoids cytochrome P450 family 26 subfamily A member 1 Homo sapiens
5 These data support the role of CYP26A1 to clear bioactive retinoids, and suggest that the enzyme forming active 4-oxo-atRA may be important in modulating retinoid action. Retinoids cytochrome P450 family 26 subfamily A member 1 Homo sapiens