Title : HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy.

Pub. Date : 2015 Jan 28

PMID : 25490467






1 Functional Relationships(s)
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1 RESULTS: We demonstrate that the C-terminal part of Vif interacts directly with LC3B, independently of the presence of APOBEC3G.Vif binds to pro-LC3 and autophagy-related protein 4-cleaved LC3 forms, and glycine 120, the amino acid conjugated to phosphatidylethanolamine on autophagosomes, is required. Glycine microtubule associated protein 1 light chain 3 beta Homo sapiens