Title : Resveratrol inhibits β-amyloid-induced neuronal apoptosis via regulation of p53 acetylation in PC12 cells.

Pub. Date : 2015 Apr

PMID : 25483559






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Resveratrol inhibits beta-amyloid-induced neuronal apoptosis via regulation of p53 acetylation in PC12 cells. Resveratrol Wistar clone pR53P1 p53 pseudogene Rattus norvegicus
2 It was demonstrated that resveratrol exerted neuronal protection through inhibition of cell apoptosis, which was associated with an increased acetylation level of p53. Resveratrol Wistar clone pR53P1 p53 pseudogene Rattus norvegicus
3 In accordance with this effect, when the acetylation level of p53 was decreased by p53 acetylation inhibitor pifithrin-alpha, the protective effects of resveratrol were abrogated. Resveratrol Wistar clone pR53P1 p53 pseudogene Rattus norvegicus
4 In accordance with this effect, when the acetylation level of p53 was decreased by p53 acetylation inhibitor pifithrin-alpha, the protective effects of resveratrol were abrogated. Resveratrol Wistar clone pR53P1 p53 pseudogene Rattus norvegicus
5 In conclusion, it was revealed that resveratrol inhibited Abeta(25-35)-induced cell apoptosis via the acetylation of p53 in PC12 cells. Resveratrol Wistar clone pR53P1 p53 pseudogene Rattus norvegicus