Pub. Date : 1989 Aug
PMID : 2548278
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of human natural killer cell and lymphokine-activated killer cell cytotoxicity and differentiation by vitamin D3. | Cholecalciferol | interleukin 2 | Homo sapiens |
| 2 | The effect of vitamin D3 and 1,25(OH)2D3 on human natural killer (NK) cells and their activation by interferon (IFN) and interleukin 2 (IL-2) was investigated. | Cholecalciferol | interleukin 2 | Homo sapiens |
| 3 | Vitamin D3 inhibited both IFN and IL-2 activation of NK activity. | Cholecalciferol | interleukin 2 | Homo sapiens |
| 4 | However, increasing doses of IL-2 were able to abrogate the inhibition caused by vitamin D3. | Cholecalciferol | interleukin 2 | Homo sapiens |
| 5 | Vitamin D3 was able to inhibit NK activity of phytohaemagglutinin and IL-2-activated cells, and also inhibit the proliferation and lymphokine-activated killer activity induced by IL-2. | Cholecalciferol | interleukin 2 | Homo sapiens |
| 6 | Vitamin D3 was able to inhibit NK activity of phytohaemagglutinin and IL-2-activated cells, and also inhibit the proliferation and lymphokine-activated killer activity induced by IL-2. | Cholecalciferol | interleukin 2 | Homo sapiens |
| 7 | Vitamin D3 was able to inhibit NK activity of phytohaemagglutinin and IL-2-activated cells, and also inhibit the proliferation and lymphokine-activated killer activity induced by IL-2. | Cholecalciferol | interleukin 2 | Homo sapiens |
| 8 | NA cells pretreated with low doses of IL-2 were sensitive to inhibition by vitamin D3 while those pretreated with high doses of IL-2 were not. | Cholecalciferol | interleukin 2 | Homo sapiens |