Title : Chemokine receptors and cortical interneuron dysfunction in schizophrenia.

Pub. Date : 2015 Sep

PMID : 25464914






3 Functional Relationships(s)
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Protein Name
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1 Alterations in inhibitory (GABA) neurons, including deficiencies in the GABA synthesizing enzyme GAD67, in the prefrontal cortex in schizophrenia are pronounced in the subpopulations of neurons that contain the calcium-binding protein parvalbumin or the neuropeptide somatostatin. gamma-Aminobutyric Acid parvalbumin Homo sapiens
2 Alterations in inhibitory (GABA) neurons, including deficiencies in the GABA synthesizing enzyme GAD67, in the prefrontal cortex in schizophrenia are pronounced in the subpopulations of neurons that contain the calcium-binding protein parvalbumin or the neuropeptide somatostatin. gamma-Aminobutyric Acid parvalbumin Homo sapiens
3 The presence of similar illness-related deficits in the transcription factor Lhx6, which regulates prenatal development of parvalbumin and somatostatin neurons, suggests that cortical GABA neuron dysfunction may be related to disturbances in utero. gamma-Aminobutyric Acid parvalbumin Homo sapiens