Title : Organocatalyzed solvent free an efficient novel synthesis of 2,4,5-trisubstituted imidazoles for α-glucosidase inhibition to treat diabetes.

Pub. Date : 2015 Feb

PMID : 25462626






2 Functional Relationships(s)
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1 A new and efficient solvent free synthesis of 2,4,5-trisubstituted imidazoles (3a-3j) was achieved by N-acetyl glycine (NAG) catalyzed three components condensation of aldehydes, benzil and ammonium acetate. Aldehydes N-acetyl-alpha-glucosaminidase Homo sapiens
2 A new and efficient solvent free synthesis of 2,4,5-trisubstituted imidazoles (3a-3j) was achieved by N-acetyl glycine (NAG) catalyzed three components condensation of aldehydes, benzil and ammonium acetate. Aldehydes N-acetyl-alpha-glucosaminidase Homo sapiens