Title : Histidine-15: an important role in the cytotoxic activity of human tumor necrosis factor.

Pub. Date : 1989 May

PMID : 2546145






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 TNF contains three histidine residues, located at positions 15, 73 and 78. Histidine tumor necrosis factor Homo sapiens
2 The histidine-specific reagent diethylpyrocarbonate (DEP) was used to chemically modify TNF. Histidine tumor necrosis factor Homo sapiens
3 The data show that the histidine residue at position 15 is an amino acid that is required for the cytotoxic activity of TNF. Histidine tumor necrosis factor Homo sapiens