Title : The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response.

Pub. Date : 2015 Jan

PMID : 25451162






1 Functional Relationships(s)
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1 We identified 2984 CG sites across the genome with unique loss of DNA methylation in double negative T cells, and showed significant reduction in mRNA expression of DNA methyltransferases DNMT1, DNMT3A, and DNMT3B. cysteinylglycine DNA methyltransferase 3 alpha Homo sapiens